Publications

Select PUBLICATIONS

Genome-Wide Epistatic Interaction between DEF1B and APOL1 High-Risk Genotypes for Chronic Kidney Disease

Vy HMT, Lin BM, Gulamali FF, Kooperberg C, Graff M, Wong J, Campbell KN, Matise TC, Coresh J, Thomas F, Reiner AP, Nassir R, Schnatz PF, Johns T, Buyske S, Haiman C, Cooper R, Loos RJF, Horowitz CR, Gutierrez OM, Do R, Franceschini N, Nadkarni GN.

Clin J Am Soc Nephrol. 2022 Aug 10;17(10):1522-5. doi: 10.2215/CJN.03610322. Online ahead of print. PMID: 35948364

Podocyte Foot Process Effacement Precedes Albuminuria and Glomerular Hypertrophy in CD2-Associated Protein Deficient Mice.

Basgen JM, Wong JS, Ray J, Nicholas SB, Campbell KN.

Front Med (Lausanne). 2021 Sep 10;8:745319. doi: 10.3389/fmed.2021.745319. eCollection 2021. PMID: 34568396

Repository Corticotropin Injections Promote Clinical Remission and Regulatory T Cell Expansion in Membranous Nephropathy.

Hartzell S, Sanchez-Russo L, Pecchio IP, Okoroafor I, Meliambro K, Bin S, Fribourg M, Cantarelli C, Campbell KN, Cravedi P.

Kidney Int Rep. 2021 Jun 22;6(9):2491-2495. doi: 10.1016/j.ekir.2021.06.010. eCollection 2021 Sep. PMID: 34514212

Plasminogenuria is associated with podocyte injury, edema, and kidney dysfunction in incident glomerular disease.

Egerman MA, Wong JS, Runxia T, Mosoyan G, Chauhan K, Reyes-Bahamonde J, Anandakrishnan N, Wong NJ, Bagiella E, Salem F, Meliambro K, Li H, Azeloglu EU, Coca SG, Campbell KN, Raij L.

FASEB J. 2020 Dec;34(12):16191-16204. doi: 10.1096/fj.202000413R. Epub 2020 Oct 18. PMID: 33070369

LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments.

Ge X, Zhang T, Yu X, Muwonge AN, Anandakrishnan N, Wong NJ, Haydak JC, Reid JM, Fu J, Wong JS, Bhattacharya S, Cuttitta CM, Zhong F, Gordon RE, Salem F, Janssen W, Hone JC, Zhang A, Li H, He JC, Gusella GL, Campbell KN, Azeloglu EU.

PMID: 32737144 PMCID: PMC7609000 DOI: 10.1681/ASN.2019121261

Disruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity.

Calizo RC, Bhattacharya S, van Hasselt JGC, Wei C, Wong JS, Wiener RJ, Ge X, Wong NJ, Lee JJ, Cuttitta CM, Jayaraman G, Au VH, Janssen W, Liu T, Li H, Salem F, Jaimes EA, Murphy B, Campbell KN, Azeloglu EU.

Nat Commun. 2019 May 3;10(1):2061. doi: 10.1038/s41467-019-09936-x. PMID: 31053734

YAP promotes cell survival by inhibiting pro-apoptotic dendrin signaling.

Campbell, K.N., Wong, J.S., Gupta, R., Asanuma, K., Sudol, M, He, J.C., and Mundel, P.

J. Biol. Chem. 2013 June 14;288 (24):17057-62. PMID: 23667252

Podocyte-specific deletion of Yes-associated protein causes focal segmental glomerulosclerosis and progressive renal failure.

Schwartzman, M, Reginensi, A, Wong, J, Basgen, J, Meliambro K., Nicholas, S., D’Agati, V, McNeill, H and Campbell, K.N.

J Am Soc Neph. 2016. Jan; 27(1):216-26 PMID: 26015453

The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A.

Faul, C, Donnelly, M., Chang, Y.H., Franz, F., Merscher-Gomez, S., Delfgaauw, J., Chang, J.M., Choi, H.Y., Campbell, K.N., Kim, K, Reiser, J., and Mundel, P.

Nat Med 2008 Sep;14(9):931-8 PMID: 18724379

DUET: A Phase 2 Study Evaluating the Efficacy and Safety of Sparsentan in Patients with FSGS

Trachtman, H, Nelson, P, Adler H, Campbell, KN, Chaudhuri, A, Derebail, V, Gambaro, G, Gesualdo, L, Gipson, D, Hogan, J, Lieberman, K, Marder, B, Meyers, K, Mustafa, E, Radhakrishnan, J, Srivastava, T, Stepanians, M, Tesar, V, Zhdanova, O and Komers R.

J Am Soc Nephrol 2018. Nov; 29 (11):2745-2754. PMID: 30361325

The Hippo pathway regulator KIBRA promotes podocyte injury by inhibiting YAP signaling and disrupting actin cytoskeletal dynamics

Meliambro, K., Wong JS, Ray, J, Calizo, R, Towne, S, Cole, B, Salem, F., Gordon, R, Kaufman, L, He, JC, Azeloglu, E and Campbell KN.

J Biol Chem. 2017. Dec 22, 292 (51): 21137-21148. PMID: 28982981